ABSTRACT
Human spleen, though being the largest component of reticuloendothelial system, is a very rare site of tumor metastases. Splenic metastases are usually seen as part of multi-organ involvement. Autopsy study conducted over a period of 10 years revealed that the incidence of neoplastic involvement of spleen was 1.45% (70/4812). Primary malignant involvement of spleen was also noted to be a rare entity in present study.
Subject(s)
Adenocarcinoma/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Autopsy , Child , Child, Preschool , Female , Humans , Incidence , Lung Neoplasms/pathology , Lymphoma/pathology , Male , Middle Aged , Spleen/pathology , Splenic Neoplasms/epidemiologyABSTRACT
Pneumocystis carinii pneumonia (PCP) has been reported as one of the opportunistic pathogens in AIDS. The significance of this pathogen in AIDS is well established so that, the diagnosis of PCP in an adult simultaneously establishes the diagnosis of AIDS. This point is well emphasised in the CDC case definition of AIDS. In western literature, the occurrence of PCP in AIDS is widely reported. However, in Indian literature only sporadic case reports have been documented. This study reports 5 cases of PCP encountered amongst 34 AIDS-autopsies studied. PCP alone was present in 2 cases. It is worth noting that it was simultaneously associated with cryptococcosis, tuberculosis and CMV in 3 remaining cases, highlighting the need for extensive investigations even after establishing the diagnosis of PCP in a known full blown AIDS patient.